Dermal fillers can be either natural or synthetic. If you have sensitive skin, natural fillers may be a better choice, as they use ingredients found in your body and are less likely to cause reactions. FDA-approved natural fillers, like Juvederm, Voluma, Restylane, and Belotero, contain hyaluronic acid or collagen. They plump and correct skin contours and last from 6 months to several years with occasional touch-ups. Temporary swelling or bruising may occur but usually fades in a few days.