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CAS No.1260141-27-2 Fumarate Vonoprazan
Vonoprazan Fumarate (TAK-438 CAS No.1260141-27-2), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan fumarate fda approval is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease.

Synonym

Vonaprazan fumarate; 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine2-butenedioate(Vonoprazan); 1-[5-(2-fluorophenyl)-1-pyridin-3-Chemicalbookylsulfonylpyrrol-3-yl]-N-methylmethanamine; AK-438; Vonaprazan(TAK-438); vonoprazan(tak-438); Vonoprazanfumarate(TAK-438); vonoprazan(tak-438)1260141-27-2.