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In 1998, iohexol 300 Injection was launched as Beilu&#039;s 1st iodinated Contrast Media. <br>Product name: Iohexol Injection <br>Generic name: Iohexol Injection <br>Type: Injectable Contrast Media for CT/X-ray <br>Ingredients: Iohexol <br>Specification: <br>(1) 20 ml: 6 gI         (2) 50 ml: 15 gI <br>(3) 75 ml: 22.5 gI    (4) 100 ml: 30 gI <br>(5) 20 ml: 7 gI         (6) 50 ml: 17.5 gI <br>(7) 100 ml: 35 gI <br>Administration: For injection or oral use of iodinated contrast <br>Adverse reactions: See the details from the package insert <br>Shelf life: 36 months <br> <br>Indications of Iohexol Injection <br>The omnipaque iohexol is an X-ray contrast agent. It can be used for angiocardiography, arteriography, urography, enhanced CT examination inclduing cervical, thoracic and lumbar myelography, CT cisternography following intrathecal injection (i.e., an injection into the subarachnoid space); arthrography, endoscopic retrograde cholangiopancreatography (ERCP), herniography or fistulography, hysterosalpingography, sialography, percutaneous transhepatic cholangiography (PTC), sinography, gastroenterography, T-tube angiography, etc. <br>Precautions of Iohexol Injection <br>General precautions for the use of nonionic-monomer contrast agent: <br>1. Special attention should be paid to patients with allergies, asthma and adverse reactions to iodinated contrast agents. Prophylactic medications such as steroids and H1/H2 histamine receptor antagonists may be considered for these patients. <br>2. The risk of serious reactions related to this type of CT contrast agent is low. 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In view of the high risks of acute renal failure after the use of contrast agent, special attention should be paid to patients with pre-existing renal impairment and diabetes and patients with atypical globulinemia (multiple myelomatoses and Waldenstrom macroglobulinemia). <br>9. Preventive actions include: <br>Identify patients with high-risk factors. <br>Ensure patients are appropriately hydrated and, if necessary, the infusion may be maintained intravenously prior to examination until the contrast agent is cleared from the kidneys. <br>Avoid any nephrotoxic agent, oral gallbladder contrast agent, surgery for arterial occlusion, renal angioplasty or other major surgeries that increase the renal burden until the contrast agent is cleared. <br>Repeat radiographic testing is delayed until renal function returned to the pre-examination level. <br>To prevent lactic acidosis, the level of serum creatinine must be determined before intravascular injection of iodinated contrast agent into diabetic patients taking metformin. For patients with abnormal serum creatinine/renal function, metformin must be discontinued and the examinations with contrast agent must be postponed until after 48 hours of discontinuation. Metformin should be reused only after renal function and serum creatinine level are constant. In some emergency cases of patients with abnormal or unknown renal function, the physician must assess both advantages and disadvantages of using contrast agent and take precautions, such as discontinuation of metformin, adequate hydration of patients, testing of renal functions, and careful observation of symptoms of lactic acidosis. <br>There is a potential risk of transient hepatic dysfunction. Special attention should be paid to patients with serious hepatic and renal insufficiency due to significantly longer time to clear contrast agent. Hemodialysis patients may receive the examinations with contrast agents. 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